A Chicken Tapasin ortholog can chaperone empty HLA-B∗37:01 molecules independent of other peptide-loading components.
Georgia F. Papadaki, Claire H. Woodward, Michael C. Young, Trenton J. Winters, George M. Burslem, and Nikolaos G. Sgourakis
Journal of Biological Chemistry October 2023
HLA3DB: comprehensive annotation of peptide/HLA complexes enables blind structure prediction of T cell epitopes
Sagar Gupta, Santrupti Nerli, Sreeja Kutti Kandy, Glenn L. Mersky & Nikolaos G. Sgourakis
Nature Communications 10 October 2023
Bioinspired 3D microprinted cell scaffolds: integration of graph theory to recapitulate complex network wiring in lymph nodes.
Matthew H. W. Chin, Barry Reid, Veronika Lachina, Sophie E. Acton, Marc-Olivier Coppens
Biotechnology Journal 20 November 2023
Structural principles of peptide-centric Chimeric Antigen Receptor recognition guide therapeutic expansion
Yi Sun, Tyler J. Florio, Sagar Gupta, Michael C. Young, Quinlen F. Marshall, Samuel E. Garfinkle, Georgia F. Papadaki, Hau V. Truong, Emily Mycek, Peiyao Li, Alvin Farrel, Nicole L. Church, Shereen Jabar, Matthew D. Beasley, Ben R. Kiefel, Mark Yarmarkovich, Leena Mallik, John M. Maris, Nikolaos G. Sgourakis
Science Immunology 1 December 2023
Conformational plasticity of RAS Q61 family of neoepitopes results in distinct features for targeted recognition
Andrew C. McShan, David Flores-Solis, Yi Sun, Samuel E. Garfinkle, Jugmohit S. Toor, Michael C. Young & Nikolaos G. Sgourakis
Nature Communications 1 December 2023